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The antibody against aur was raised in rabbit using the Recombinant Staphylococcus aureus Zinc metalloproteinase aureolysin (aur) (210-509AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein A/G purified. This antibody has been validated on ELISA, WB.
The antibody against aur was raised in rabbit using the Recombinant Staphylococcus aureus Zinc metalloproteinase aureolysin (aur) (210-509AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein A/G purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-01731A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | aur |
| Target Synonyms | aur antibody; Zinc metalloproteinase aureolysin antibody; EC 3.4.24.29 antibody; Staphylococcus aureus neutral proteinase antibody | Form | Liquid |
| Species Reactivity | Staphylococcus aureus | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Protein A/G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Staphylococcus aureus Zinc metalloproteinase aureolysin (aur) (210-509AA) | Target Species | Staphylococcus aureus |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P81177 |
Uniprot Id
P81177
Target Species
Staphylococcus aureus
Target Name
AUR
Target Function
Plays an essential role in immune evasion by helping bacteria to resist complement-mediated killing by neutrophils. Inhibits the deposition of host C3b on bacterial surfaces and the release of the chemoattractant C5a by cleaving the central complement protein C3. The cleavage site renders the C3b molecule vulnerable to proteolytic degradation by host regulators. Cleaves and inactivates host SERPINA1, which is an endogenous protease inhibitor essential for controlling neutrophil serine protease elastase. Plays also an essential role in the cleavage and subsequent activation of the serine protease SspA which is involved in colonization and infection of human tissues.
Target Protein Families
Peptidase M4 family
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