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The antibody against speB was raised in rabbit using the Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against speB was raised in rabbit using the Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-11904A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | speB |
| Form | Liquid | Species Reactivity | Streptococcus pyogenes serotype M28 |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA) | Target Species | Streptococcus pyogenes serotype M28 |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q48R29 |
Uniprot Id
Q48R29
Target Species
Streptococcus pyogenes serotype M28
Target Name
SPEB
Target Function
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing.
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase C10 family
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