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The recombinant antibody against THEMIS was produced using a synthesized peptide derived from Human THEMIS as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, IF, FC.
The recombinant antibody against THEMIS was produced using a synthesized peptide derived from Human THEMIS as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, IF, FC.
$350.00
| Cat.No | ADC-56538A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | THEMIS | Target Synonyms | C6orf190 C6orf207, Protein THEMIS (Thymocyte-expressed molecule involved in selection), THEMIS |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, FC | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from Human THEMIS | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N1K5 |
Uniprot Id
Q8N1K5
Target Species
Human
Target Name
THEMIS
Target Full Name
Protein THEMIS
Target Function
Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
Themis family
Target Synonyms
C6orf190; C6orf207; MGC163388; Protein THEMIS; SIGNALING PHOSPHOPROTEIN SPECIFIC FOR T CELLS; SPOT; THEMIS; THMS1_HUMAN; Thymocyte expressed molecule involved in selection; Thymocyte selection associated; Thymocyte selection pathway associated; Thymocyte-expressed molecule involved in selection; TSEPA
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