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The recombinant antibody against TNNT2 was produced using a synthesized peptide derived from Human TNNT2 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, FC.
The recombinant antibody against TNNT2 was produced using a synthesized peptide derived from Human TNNT2 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, FC.
$350.00
| Cat.No | ADC-56570A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | TNNT2 | Target Synonyms | cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT), TNNT2, Troponin T |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, FC | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from Human TNNT2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P45379 |
Uniprot Id
P45379
Target Species
Human
Target Name
TNNT2
Target Full Name
Troponin T, cardiac muscle
Target Function
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Target Involvement
Cardiomyopathy, familial hypertrophic 2 (CMH2); Cardiomyopathy, dilated 1D (CMD1D); Cardiomyopathy, familial restrictive 3 (RCM3)
Target Protein Families
Troponin T family
Target Tissue Specificity
Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in
Target Synonyms
CMH2; RCM3; TnTC; cTnT; CMD1D; CMPD2; LVNC6; Cardiac troponin T (TNNT2)
Target Background
This gene encodes the cardiac isoform of troponin T. The encoded protein is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy.
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