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The recombinant antibody against TUBB1 was produced using the Recombinant Human TUBB1 protein as the immunogen. This antibody exists as a non-conjugated isotype Mouse IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC, FC.
The recombinant antibody against TUBB1 was produced using the Recombinant Human TUBB1 protein as the immunogen. This antibody exists as a non-conjugated isotype Mouse IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC, FC.
$350.00
Western Blot | Positive WB detected in: K562 whole cell lysate | All lanes: TUBB1 antibody at 1:1000 | Secondary | Goat polyclonal to mouse IgG at 1/50000 dilution | Predicted band size: 50 kDa | Observed band size: 50 kDa
| Cat.No | ADC-56455A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | TUBB1 | Target Synonyms | 2810484G07Rik antibody; beta 1 tubulin antibody; Beta tubulin 1, beta 1 antibody; tubulin, beta1 antibody |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Mouse IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB, FC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human TUBB1 protein | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H4B7 |
Uniprot Id
Q9H4B7
Target Species
Human
Target Name
TUBB1
Target Full Name
Tubulin beta-1 chain
Target Function
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Target Involvement
Macrothrombocytopenia, autosomal dominant, TUBB1-related (MAD-TUBB1)
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Protein Families
Tubulin family
Target Tissue Specificity
Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins.
Target Synonyms
2810484G07Rik; beta 1 tubulin; Beta tubulin 1, class VI; Beta-tubulin; Class VI beta tubulin; dJ543J19.4; M(beta)1; TBB1_HUMAN; TUBB1; Tubulin beta 1 class VI; Tubulin beta-1 chain; Tubulin, beta 1; tubulin, beta1
Target Background
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.
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