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The recombinant antibody against USP24 was produced using a synthesized peptide derived from human USP24 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IF, FC.
The recombinant antibody against USP24 was produced using a synthesized peptide derived from human USP24 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IF, FC.
$350.00
| Cat.No | ADC-56649A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | USP24 | Target Synonyms | KIAA1057, Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24), USP24 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, FC | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from human USP24 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UPU5 |
Uniprot Id
Q9UPU5
Target Species
Human
Target Name
USP24
Target Full Name
Ubiquitin carboxyl-terminal hydrolase 24
Target Function
Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron.
Target Protein Families
Peptidase C19 family
Target Synonyms
Deubiquitinating enzyme 24; KIAA1057; Ubiquitin carboxyl terminal hydrolase 24; Ubiquitin carboxyl-terminal hydrolase 24; Ubiquitin specific peptidase 24; Ubiquitin specific processing protease 24; Ubiquitin specific protease 24; Ubiquitin thioesterase 24; Ubiquitin thiolesterase 24; Ubiquitin-specific-processing protease 24; UBP24_HUMAN; Usp24
Target Background
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).
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