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Rabbit anti-Zebrafish rbm24 Polyclonal Antibody

The antibody against rbm24 was raised in rabbit using the Recombinant Zebrafish RNA-binding protein 24 protein (2-78AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-03272A

The antibody against rbm24 was raised in rabbit using the Recombinant Zebrafish RNA-binding protein 24 protein (2-78AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-03272A ClonalityPolyclonal
Host SpeciesRabbitTarget Namerbm24
Target Synonymsrbm24 antibody; RNA-binding protein 24 antibody; RNA-binding motif protein 24 antibody; RNA-binding protein SEB-4 antibodyFormLiquid
Species ReactivityZebrafishIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Zebrafish RNA-binding protein 24 protein (2-78AA)Target SpeciesZebrafish
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ76LC6
Background Information
  • Uniprot Id

    Q76LC6

  • Target Species

    Zebrafish

  • Target Name

    RBM24

  • Target Function

    Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes. Plays a role in the regulation of mRNA stability and mRNA translation to which it is bound. Involved in myogenic differentiation by regulating myog levels. Binds to a huge amount of mRNAs. Required for embryonic heart development, sarcomer and M-band formation in striated muscles.

  • Target Subcellular Location

    Nucleus. Cytoplasm.

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