U6 Snrna-Associated Sm-Like Protein Lsm6 (LSM6) Reagents

U6 snRNA-associated Sm-like protein LSm6

Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable).

Cytoplasm. Nucleus.

SnRNP Sm proteins family, SmF/LSm6 subfamily

LSM6U6 snRNA-associated Sm-like protein LSm6