Rap1 Gtpase-Gdp Dissociation Stimulator 1 (RAP1GDS1) Reagents

Rap1 GTPase-GDP dissociation stimulator 1

Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein. Able to promote the Ca(2+) release from the endoplasmic reticulum via both inositol trisphosphate (Ins3P) and ryanodine sensitive receptors leading to a enhanced mitochondrial Ca(2+) uptake.

Cytoplasm, cytosol. Endoplasmic reticulum. Mitochondrion.

Exchange factor smgGDS; GDP dissociation stimulator 1; GDS1; GDS1_HUMAN; GTP-GDP dissociation stimulator 1; GTPase-GDP dissociation stimulator; Rap1; 1; Highly similar to RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1; MGC118859; MGC118861; RAP1; Rap1 GTPase-GDP dissociation stimulator 1; RAP1GDS1; SMG GDS protein; SMG P21 stimulatory GDP/GTP exchange protein; SMGGDS